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2-Bromobutyric acid

  • Product Name: 2-Bromobutyric acid
  • CasNo: 80-58-0
  • Purity:
  • Appearance: clear yellow liquid

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CasNo: 80-58-0

Molecular Formula: C4H7BrO2

Appearance: clear yellow liquid

High Quality Chinese Factory supply 80-58-0 2-Bromobutyric acid

  • Molecular Formula:C4H7BrO2
  • Molecular Weight:167.002
  • Appearance/Colour:clear yellow liquid 
  • Vapor Pressure:0.0533mmHg at 25°C 
  • Melting Point:-4 °C 
  • Refractive Index:n20/D 1.474(lit.)  
  • Boiling Point:216.6 °C at 760 mmHg 
  • PKA:pK1: 2.939 (35°C) 
  • Flash Point:84.8 °C 
  • PSA:37.30000 
  • Density:1.625 g/cm3 
  • LogP:1.24450 

2-Bromobutyric acid(Cas 80-58-0) Usage

2-Bromobutyric acid is the organic compound, which is a colorless liquid. 2-Bromobutyric acid was used in the synthesis of S-(1-carboxypropyl)-L-cysteine.

InChI:InChI=1/C4H7BrO2/c1-2-3(5)4(6)7/h3H,2H2,1H3,(H,6,7)/p-1/t3-/m0/s1

80-58-0 Relevant articles

O-to-S Substitution Enables Dovetailing Conflicting Cyclizability, Polymerizability, and Recyclability: Dithiolactone vs. Dilactone

Chen, Jinlong,Li, Maosheng,Tao, Youhua,Wang, Xianhong,Wang, Yanchao

supporting information, p. 22547 - 22553 (2021/09/09)

Developing chemically recyclable polymer...

Method for preparing alpha-bromo fatty acid ester

-

Paragraph 0020-0021; 0023-0024, (2019/04/04)

The invention provides a method for prep...

Reaction of Lithium Acylate α-Carbanions with Carbon Tetrabromide

Zorin,Zaynashev,Zorin

, p. 1527 - 1531 (2019/12/28)

Lithium acylate α-carbanions generated b...

Catalytic Asymmetric Conjugate Addition and Sulfenylation of Diarylthiazolidin-2,4-diones

Jiao, Lihui,Bu, Liwei,Ye, Xinyi,Zhao, Xiaowei,Jiang, Zhiyong

, p. 9620 - 9629 (2016/11/02)

This work reports the first application ...

80-58-0 Process route

butyric acid
107-92-6

butyric acid

2-Bromobutyric acid
80-58-0

2-Bromobutyric acid

rac-2,3-diethylsuccinic acid
1186-79-4

rac-2,3-diethylsuccinic acid

Conditions
Conditions Yield
butyric acid; With lithium diisopropyl amide; In tetrahydrofuran; at 20 - 25 ℃; Inert atmosphere;
With carbon tetrabromide; In tetrahydrofuran; at 20 - 25 ℃; Inert atmosphere;
79%
12%
butyric acid; With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 40 ℃; Inert atmosphere;
With N,N-diethyl-N-bromoamine; In tetrahydrofuran; at 20 - 25 ℃; for 2h; Inert atmosphere;
47%
34%
butyric acid; With lithium diisopropyl amide; In tetrahydrofuran; at 20 - 25 ℃; Inert atmosphere;
With carbon tetrabromide; In tetrahydrofuran; at 20 - 25 ℃; Inert atmosphere;
25%
43%
butyric acid
107-92-6

butyric acid

2-Bromobutyric acid
80-58-0

2-Bromobutyric acid

Conditions
Conditions Yield
With N-Bromosuccinimide; sulfuric acid; In trifluoroacetic acid; at 85 ℃; for 16h;
87%
With bromine; phosphorus trichloride; for 4.5h; Heating;
78%
With phosphorus; bromine; Behandeln des entstandenen 2-Brom-buttersaeure-bromids mit Wasser;
 
With phosphorus; bromine; at 100 ℃; Zersetzen des gebildeten Bromids mit kochendem Wasser;
 
With bromine;
 
With bromine; sulfur;
 
With hydrogen bromide; bromine; at 120 ℃;
 
With phosphorus; bromine;
 
With phosphorus; bromine; heisses Wasser eintropfen,nach dem Erkalten von dem ausgeschiedenen Oel abgiessen,mit Aether ausschuetteln;die aetherischen Auszuege werden verdampft und der Rueckstand im Vakuum destilliert;
 
With PPA; water; bromine;
 
With bromine; phosphorus trichloride; at 80 - 100 ℃; for 15h;
 
With chlorosulfonic acid; bromine; In 1,2-dichloro-ethane; at 85 ℃; for 2h;
 
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; for 2h; Reflux;
 
With N-Bromosuccinimide; bromine; at 90 - 100 ℃; for 2h; Time; Large scale;
 

80-58-0 Upstream products

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    butanoic acid anhydride

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    (2R)-2-bromobutanoic acid

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    bromoethylmalonic acid

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    5076-24-4

    silver butyrate

80-58-0 Downstream products

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    propyl 2-bromobutanoate

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    2-(1-methyl-1H-benzimidazol-2-ylmercapto)-butyric acid

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    533-68-6

    2-bromobutyric acid ethyl ester

  • 113104-28-2
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    2-(4-tert-butyl-phenoxy)-butyric acid

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