Reliable factory customized supply 1-Bromo-2-methylpropane 78-77-3
- Molecular Formula:C4H9Br
- Molecular Weight:137.019
- Appearance/Colour:clear liquid
- Vapor Pressure:41 hPa (20 °C)
- Melting Point:-119 °C
- Refractive Index:n20/D 1.435(lit.)
- Boiling Point:90.7 °C at 760 mmHg
- Flash Point:18.3 °C
- PSA：0.00000
- Density:1.26 g/cm3
- LogP:2.03730
1-Bromo-2-methylpropane(Cas 78-77-3) Usage
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Safety Profile
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Questionable
carcinogen with experimental neoplastigenic
data. Moderately toxic by intraperitoneal
route. A dangerous fire hazard when
exposed to heat or flame. When heated to
decomposition it emits toxic fumes of Br-.
See also BROMIDES. |
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Purification Methods
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Partially hydrolyse it to remove any tertiary alkyl halide, then fractionally distil it, then wash it with conc H2SO4, water and aqueous K2CO3, then redistil it from dry K2CO3. [Dunbar & Hammett J Am Chem Soc 72 109 1950, Beilstein 1 IV 294.] |
InChI:InChI=1/C4H9Br/c1-4(2)3-5/h4H,3H2,1-2H3
78-77-3 Relevant articles
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Noller,Dinsmore
, p. 1025,1028, 1030 (1932)
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New preparation method of febuxostat intermediate
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Paragraph 0098-0100, (2020/03/06)
The invention relates to a new preparati...
PROCESSES FOR MAKING ALKYL HALIDES
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Page/Page column 8, (2010/09/18)
The invention is directed to processes f...
Scavenger assisted combinatorial process for preparing libraries of tertiary amine compounds
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, (2008/06/13)
This invention relates to a novel soluti...
Kinetics and thermochemistry of the R + HBr ? RH + Br (R = n-C3H7, isoC3H7, n-C4H9, isoC4H9, sec-C4H9 or tert-C4H9) equilibrium
Seetula, Jorma A.,Slagle, Irene R.
, p. 1709 - 1719 (2007/10/03)
The kinetics of the reactions of n-C3H7,...
78-77-3 Process route
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75-28-5,40921-86-6
Isobutane
Conditions
| Conditions |
Yield |
|
With
norborn-2-ene; N-bromobis(trimethylsilyl)amine;
at 44.9 ℃;
for 2h;
Product distribution;
Mechanism;
Irradiation;
variation of temperature, time, reagent concentration, initiation method;
|
|
|
With
N-Bromosuccinimide;
In
dichloromethane;
at 15 ℃;
Product distribution;
Irradiation;
CH2CCl2; influence of additive - BrCCl3;
|
|
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With
N-Bromosuccinimide; 1,1-Dichloroethylene;
In
dichloromethane;
at 14 - 15 ℃;
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0.084 mmol
0.133 mmol
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-
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106-97-8,9003-29-6,9021-92-5
n-butane
-
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78-76-2,5787-31-5
s-butyl bromide
Conditions
| Conditions |
Yield |
|
With
2AlBr3*CBr4; bromine;
at -20 ℃;
for 2h;
Title compound not separated from byproducts;
|
|
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With
2AlBr3*CBr4; bromine;
In
various solvent(s);
at -20 ℃;
for 2h;
Yields of byproduct given. Title compound not separated from byproducts;
|
|
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With
2AlBr3*CBr4; bromine;
at -20 ℃;
for 2h;
Yield given. Title compound not separated from byproducts;
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|
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With
2AlBr3*CBr4; bromine;
In
various solvent(s);
at -20 ℃;
for 2h;
Yield given. Title compound not separated from byproducts;
|
|
78-77-3 Upstream products
78-77-3 Downstream products
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